This research attempts to understand the linkages between quarantine, trade and diplomacy during the plague pandemic of 1897 in colonial India with special reference to Game Presidency. For the purpose of this seminar, we will be focusing on the third objective of this research which deals with International Sanitary Conferences (ISCs) and their interaction with British epidemic policy-making. ISCs were a series of fourteen conferences held between 1851–1938 with the objective of protecting Europe and standardising epidemic regulations against cholera, plague and yellow fever. This study focuses on the sanitary regimes formed by the four ISCs convened in the 1890s (1892, 1893, 1894 and 1897) and highlights the scheme of regulations that were instituted to standardise epidemic regulations. It examines the interaction of ISCs with British epidemic policy-making in colonial India in two ways. First, it throws light on the interactions between the ISC of 1894 and the movement of pilgrims to Mecca from colonial India. It highlights the views of Surgeon General Cunningham (Indian delegate) in the discussions of the conference. It also looks into the objections that were conveyed by the Government of India to the British government against the regulations adopted at the ISC of 1894. Second, it attempts to demonstrate the linkages between global, regional and local levels. The regulations formed at ISC of 1897 and its impact on the Epidemic Diseases Act (1897) that was passed to control the spread of plague in British India is analysed. The regulations adopted in Game Presidency which were in concurrence with ISC of 1897 are examined in detail. This objective argues that these linkages were dynamic in nature with regional factors playing an important role in formation of international epidemic policies.