The direct conversion of B-H bonds to substituted vertices is an attractive strategy for the synthesis
of cage compounds with desired properties. However, compared to C-H functionalization, boron
functionalization is less explored. The most known approach of B−H functionalization is substitution
leading to the alkylation, hydroxylation or halogenation and their further organic transformations [1].
These functionalizations lead to the formation of molecules having applications ranging from materials
science to medicine [2]. Though the electrophilic substitution of hydrogen at B−H vertices of the boranes
or carboranes is well-known, the exo-cluster substitution of metallaboranes differs markedly and there
are only few examples are known in the literature [3]. In this seminar, the synthesis, properties and
applications of various functionalized boron clusters as well as preliminary result of my research work in
this field will be discussed.
References:
[1]. (a) T. Peymann, A. Herzog, C. B. Knobler and M. F. Hawthorne, Angew. Chem., Int. Ed., 1999, 38, 1062−1064;
(b) A. Maderna, C. B. Knobler and M. F. Hawthorne, Angew. Chem., Int. Ed., 2001, 40,1662−1664
[2]. (a) A. H. Soloway, W. Tjarks, B. A. Barnum, F. G. Rong, R. F. Barth, I. M. Codogni and J. G. Wilson, Chem. Rev., 1998,
98, 1515−1562; (b) C. A. Reed, Acc. Chem. Res., 1998, 31, 133−139.
[3]. (a) B. L. Guennic, H. Jiao, S. Kahlal, J. -Y. Saillard, J. -F. Halet, S. Ghosh, M. Shang, A. M. Beatty, A. L. Rheingold and T.
P. Fehlner, J. Am. Chem. Soc., 2004, 126, 3203−3217; (b) S. Sahoo, K. H. K. Reddy, R. S. Dhayal, S. M. Mobin, V.
Ramkumar, E. D. Jemmis, and S. Ghosh, Inorg. Chem., 2009, 48, 65096516; (c) R. Prakash, K. Bakthavachalam, B.
Varghese and S Ghosh, J. Organomet. Chem., 2017, 846, 372-378.