This research proposes an efficient algorithm for simulating wave-structure interaction with two-phase Computational Fluid Dynamics (CFD) solvers. The algorithm is based on the coupling of potential wave theory and two- phase Navier-Stokes equations. It is an extension of the Spectral Wave Explicit Navier-Stokes Equations (SWENSE) method for generalized two-phase CFD solvers with interface capturing techniques. In this algorithm, the total solution is decomposed into an incident and a complementary component. The incident solution is explicitly obtained with spectral wave models based on potential flow theory; only the complementary solution is solved with CFD solvers, representing the influence of the structure on the incident waves. The decomposition ensures the accuracy of the incident wave’s kinematics regardless of the mesh in CFD solvers. A significant reduction of the mesh size is expected in typical wave- structure interaction problems.